Protein name:
25-hydroxycholesterol 7-alpha-hydroxylase (Oxysterol 7-alpha-hydroxylase) ;
Alternative:
Oxysterol 7-alpha-hydroxylase ;Cytochrome P450 7B1 ;
Organism:
Human (Homo sapiens).
General Annotation
Subcellular Location:
Endoplasmic reticulum membrane
Peripheral membrane protein
Microsome membrane
Peripheral membrane protein
Protein Attributes:
50:
MAGEVSAATG | RFSLERLGLP | GLALAAALLL | LALCLLVRRT | RRPGEPPLIK |
100:
GWLPYLGVVL | NLRKDPLRFM | KTLQKQHGDT | FTVLLGGKYI | TFILDPFQYQ |
150:
LVIKNHKQLS | FRVFSNKLLE | KAFSISQLQK | NHDMNDELHL | CYQFLQGKSL |
200:
DILLESMMQN | LKQVFEPQLL | KTTSWDTAEL | YPFCSSIIFE | ITFTTIYGKV |
250:
IVCDNNKFIS | ELRDDFLKFD | DKFAYLVSNI | PIELLGNVKS | IREKIIKCFS |
300:
SEKLAKMQGW | SEVFQSRQDV | LEKYYVHEDL | EIGAHHLGFL | WASVANTIPT |
350:
MFWAMYYLLR | HPEAMAAVRD | EIDRLLQSTG | QKKGSGFPIH | LTREQLDSLI |
400:
CLESSIFEAL | RLSSYSTTIR | FVEEDLTLSS | ETGDYCVRKG | DLVAIFPPVL |
450:
HGDPEIFEAP | EEFRYDRFIE | DGKKKTTFFK | RGKKLKCYLM | PFGTGTSKCP |
500:
GRFFALMEIK | QLLVILLTYF | DLEIIDDKPI | GLNYSRLLFG | IQYPDSDVLF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
Protein for Human Oxysterol 7-alpha-hydroxylase
Protein for Human Oxysterol 7-alpha-hydroxylase
Protein for Human Oxysterol 7-alpha-hydroxylase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INVOLVEMENT IN CBAS3
tissue :
Liver .
tissue :
Spleen .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
tissue :
Hippocampus .
3.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
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Halpern A.L.
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Mobarry C.M.
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Walenz B.
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Shatkay H.
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Dew I.
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Miller J.R.
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Turner R.
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Yooseph S.
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Lu F.
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Eichler E.E.
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Adams M.D.
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Hunkapiller M.W.
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Myers E.W.
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Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.
"Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration."
Tsaousidou M.K.
,
Ouahchi K.
,
Warner T.T.
,
Yang Y.
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Simpson M.A.
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Laing N.G.
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Wilkinson P.A.
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Madrid R.E.
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Patel H.
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Patton M.A.
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Siddique T.
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Crosby A.H.
Am. J. Hum. Genet.82:510-515(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS SPG5A ARG-57; SER-216; PHE-363 AND HIS-417