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Index > Protein center > CYP7B1(Gene name) > Human
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  • CYP7B1 (Gene name),
  • 25-hydroxycholesterol 7-alpha-hydroxylase (Protein name ),  CP7B1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CYP7B1;
    Protein name:
    25-hydroxycholesterol 7-alpha-hydroxylase(Oxysterol 7-alpha-hydroxylase);
    Alternative:
    Oxysterol 7-alpha-hydroxylase;Cytochrome P450 7B1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N/A
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    506
    Sequence:
    50:
    MAGEVSAATG | RFSLERLGLP | GLALAAALLL | LALCLLVRRT | RRPGEPPLIK | 
    100:
    GWLPYLGVVL | NLRKDPLRFM | KTLQKQHGDT | FTVLLGGKYI | TFILDPFQYQ | 
    150:
    LVIKNHKQLS | FRVFSNKLLE | KAFSISQLQK | NHDMNDELHL | CYQFLQGKSL | 
    200:
    DILLESMMQN | LKQVFEPQLL | KTTSWDTAEL | YPFCSSIIFE | ITFTTIYGKV | 
    250:
    IVCDNNKFIS | ELRDDFLKFD | DKFAYLVSNI | PIELLGNVKS | IREKIIKCFS | 
    300:
    SEKLAKMQGW | SEVFQSRQDV | LEKYYVHEDL | EIGAHHLGFL | WASVANTIPT | 
    350:
    MFWAMYYLLR | HPEAMAAVRD | EIDRLLQSTG | QKKGSGFPIH | LTREQLDSLI | 
    400:
    CLESSIFEAL | RLSSYSTTIR | FVEEDLTLSS | ETGDYCVRKG | DLVAIFPPVL | 
    450:
    HGDPEIFEAP | EEFRYDRFIE | DGKKKTTFFK | RGKKLKCYLM | PFGTGTSKCP | 
    500:
    GRFFALMEIK | QLLVILLTYF | DLEIIDDKPI | GLNYSRLLFG | IQYPDSDVLF | 
    506:
    RYKVKS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    E10333r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    E10333m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    E10333h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    U10333m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    U10333r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    U10333h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    P10333Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    P10333Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Cat.:
    P10333Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Monoclonal Antibody for Human Oxysterol 7-alpha-hydroxylase
    Protein for Human Oxysterol 7-alpha-hydroxylase
    Protein for Human Oxysterol 7-alpha-hydroxylase
    Protein for Human Oxysterol 7-alpha-hydroxylase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7-alpha-hydroxylase gene causes severe neonatal liver disease."
      Setchell K.D.R. , Schwarz M. , O'Connell N.C. , Lund E.G. , Davis D.L. , Lathe R. , Thompson H.R. , Tyson W.R. , Sokol R.J. , Russell D.W.
      J. Clin. Invest.102:1690-1703(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INVOLVEMENT IN CBAS3
      tissue: Liver.
      tissue: Spleen.
    2. 2.
      "Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1."
      Wu Z.L. , Martin K.O. , Javitt N.B. , Chiang J.Y.L.
      J. Lipid Res.40:2195-2203(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Hippocampus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration."
      Tsaousidou M.K. , Ouahchi K. , Warner T.T. , Yang Y. , Simpson M.A. , Laing N.G. , Wilkinson P.A. , Madrid R.E. , Patel H. , Hentati F. , Patton M.A. , Hentati A. , Lamont P.J. , Siddique T. , Crosby A.H.
      Am. J. Hum. Genet.82:510-515(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SPG5A ARG-57; SER-216; PHE-363 AND HIS-417
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